Friday, March 28, 2008

Gene Mutations

A gene mutation is a permanent change in the DNA sequence that makes up a gene. One type of gene mutation is deletion. A deletion changes the number of DNA bases by removing a piece of DNA. Small deletions may remove one or a few base pairs within a gene, while larger deletions can remove an entire gene or several neighboring genes. The deleted DNA may alter the function of the resulting protein(s). Such changes in genes and proteins control why your hair might be curly rather than straight, how tall you are, and why you might be at risk for developing cancer. Cancer, for example, can occur because one or more of your body's proteins are not acting correctly. They tell your cells to do things they normally wouldn't do — like multiply out of control. One specific type of cancer is Skin Cancer. Skin cancer is the cancer that forms in the tissues. There are several different types of skin cancer. Skin cancer that forms in melanocytes (skin cells that make pigment) is called melanoma. Most skin cancers form in older people on parts of the body exposed to the sun or in people who have weakened immune systems.